CAMH PET Centre
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Instrumentation

    The facility is equipped with a 17 MeV dual particle cyclotron (Scanditronix MC-17) and a brain PET scanner (GEMS 2048-15B). The facility also houses research laboratories for the development of new PET radioligands. A new generation 3D brain PET tomograph is under construction and will be installed during the coming year.
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Radioligands

    The following radiotracers are currently used for human research:

    [15O]-water Brain activation
    [18F]-FDG Glucose metabolism
    [11C]-raclopride Dopamine D2 antagonist
    [11C]-FLB 457 High-affinity dopamine D2 antagonist
    [11C]-SCH 23390 Dopamine D1 antagonist
    [11C]-flumazenil Benzodiazepine receptor radioligand
    Carbonyl-[11C]-WAY 100635 Serotonin 5-HT1A antagonist
    [18F]-setoperone Serotonin 5-HT2A antagonist
    [11C]-DASB Serotonin transporter
    [11C]-RTI 32 Dopamine transporter Color
    [18F]-FPCIT Dopamine transporter
    [11C]-MeNER Norepinephrine transporter
    [11C]-rolipram Radioligand for the cAMP-specific phosphodiesterase-4 (PDE4)
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PET Centre, Centre for Addiction and Mental Health and University of Toronto
250 College Street, Toronto, ON, Canada M5T 1R8
Copyright © 1999-2001
Last revised at 04:55 PM on 13/05/2002